Ordering and results reporting made easy

Find out how to order the Oncoguard® Liver solution and interpret results

Oncoguard® Liver test ordering

The Oncoguard® Liver test offers the convenience of one simple blood collection that can be performed in your office or an affiliated laboratory. All you need to have on hand at the blood collection site is the Exact Sciences Blood Collection Kit and the Oncoguard® Liver test Requisition Form (RF) if you’re ordering tests manually.
Specimens are collected using the Exact Sciences Blood Collection Kit (kit).
illustration test

Convenient ordering processes that work with your workflow

The Oncoguard® Liver test can be ordered in one of two ways:

More detailed information on electronic ordering through EpicCare® LinkTM can be found in the EpicCare® LinkTM Welcome Guide in the Training and Additional Resources section within EpicCare® Link.TM
Download a fillable PDF of the Requisition Form, Statement of Medical Necessity, and ABN form from the Resources page.
Our Customer Care Center can help you with your supply orders for Blood Collection Kits, Requisition Forms, Labels and setting up an EpicCare® LinkTM account.
See the Order Supplies section for more details »

Some health plans may require prior authorization for the Oncoguard® Liver test. Prior authorization should be completed prior to specimen collection. A signed Advance Beneficiary Notice of Noncoverage (ABN) is required for standard Medicare plans.

Oncoguard® Liver test results are generated in a format that’s easy to read and understand and will typically be:

  • Available within a week from the specimens being received in our laboratory
  • Available in a patient’s chart in EpicCare® LinkTM for those providers with an EpicCare® LinkTM account, or
  • Sent via secure fax using the secure fax number included on the Order Requisition Form

High result

A high test result may indicate the presence of HCC. When a positive result is reported, additional clinical assessment to confirm the presence of HCC is suggested (e.g., diagnostic imaging procedures).


Negative result

A negative test result indicates a lower likelihood of the presence of HCC. When a negative result is obtained, a 3- to 6-month surveillance cadence is suggested.

In rare instances, a technical failure or insufficient clinical material in the sample yields an invalid result.

False positive and false negative results are possible with the Oncoguard® Liver test. In the clinical lab validation study, the false positive rate was 13% and the false negative rate was 12%.1

The Oncoguard® Liver test is a simple, yet sophisticated blood test that delivers actionable information with a single assessment.

We are here to support smooth test ordering, collection, processing, and reporting.

Contact the Customer Care Center at 1-844-870-8870 or fill out a form to request a visit with a representative.

References: 1. Chalasani NP, Porter K, Bhattacharya A, Book AJ, Neis BM, Xiong KM, Ramasubramanian TS, Edwards V DK, Chen I, Johnson S, Roberts LR, Kisiel JB, Reddy KR, Singal AG, Olson MC, Bruinsma JJ, Validation of a novel multi-target blood test shows high sensitivity to detect early-stage hepatocellular carcinoma, Clinical Gastroenterology and Hepatology (2021)